Terms of use

Jim, diagnosed with multiple myeloma

Terms of use

Millennium Pharmaceuticals, Inc. is pleased to provide you with the materials on this web site for informational purposes. Please carefully read the following paragraphs. By using our web site, you agree to the terms described below. If you do not agree to the terms discussed here, you should exit this web site now.

Millennium maintains this web site from our offices in Cambridge, Massachusetts, United States of America. This web site is intended to be accessed from, and the information contained in the web site is intended to be used within, the United States of America. We make no representations that this web site or materials in our web site are appropriate or available for access or use in other countries. If you access this web site from another country, you do so on your own initiative and are responsible for compliance with laws applicable to such access. We may revise the terms discussed here at any time without notice by updating this posting. You are bound by any revisions and, therefore, should periodically visit this page to review the current terms that apply to your use of our web site.

Intellectual Property Rights
All contents of this web site are protected by copyright and/or other intellectual property rights, and may not be modified, distributed, posted or transmitted without our prior written consent. You may download material from our web site, for your own personal, non-commercial use only. No Copyright notices, other intellectual property or legal notices or other identifying information may be removed from downloaded materials. You may not download material from our web site for any other purpose without our prior written consent.

Millennium and the Millennium logo are trademarks of Millennium Pharmaceuticals, Inc. and/or its affiliates, registered in the U.S. and/or other jurisdictions. Other Millennium product or service names or logos referenced in this document are either trademarks or registered trademarks of Millennium Pharmaceuticals, Inc. and/or its affiliates. The absence of a product or service name or logo from this list does not constitute a waiver of Millennium’s trademark or other intellectual property rights concerning that name or logo.

Other trademarks and product names are the property of their respective owners. Nothing contained in our web site should be construed as granting any license or right to use any trademarks or logos.

Submissions of Information
Any communication or material that you transmit to our site, by electronic mail or otherwise, including any data, questions, comments, suggestions or the like, is, and will be treated as, non-confidential and nonproprietary information.

Millennium may use such communication or material for any purpose whatsoever including, but not limited to, reproduction, disclosure, transmission, publication, broadcast and further posting. Further, Millennium is free, without payment of compensation to you, to use any ideas, concepts, know-how or techniques contained in any communication or material you send to our web site for any purpose whatsoever.

Concerning Your Privacy
We may monitor access to this web site. If monitored, the requesting URLs, the machine originating the request, and the time of the request, may be logged for access statistics and security purposes. By using this web site, you consent to such general monitoring. Please see Millennium’s Web Site Privacy Policy for further details on how information from the web site may be gathered and used.

Third Party Links
Periodically, our web site may contain links to other web sites. Millennium is providing these links to you only as a convenience, and the inclusion of any link does not imply endorsement by us of the third-party web site. Millennium has no control over the content on such third party web sites. Millennium does not take any responsibility or assume any liability for information contained on other web sites. Your linking to any other web sites is at your own risk, and you are responsible for learning about and complying with the terms of usage and other conditions posted on those web sites.

Medical Information/Conditions
Any information posted on our web site related to medical conditions and their treatment is general in nature and is intended only for educational and general information purposes. Should you have a medical condition that may require treatment, or if you have any specific medical questions, promptly see your own doctor or health care provider. Nothing on this web site is substitute for professional medical consultation advice. We do not offer medical diagnosis or treatment from this web site, and none of the information contained on this web site should be construed as providing medical advice or services of any kind. Only your doctor or other health care professional can determine if a particular medical treatment is appropriate for you.

Always seek the advice of your physician or other qualified health care provider before starting any new treatment or with any questions you may have about a medical condition.

Disclaimer
Millennium believes that the contents of this web site have come from reliable sources, but we cannot guarantee the information in this web site is accurate, complete or suitable for any purpose. In addition, Millennium cannot guarantee that the contents of this web site have not been affected by technical malfunctions or unauthorized tampering. The contents of this web site are subject to change without notice. We may alter or delete material from this web site at any time.

Your use of this web site and its contents is at your own risk, and neither Millennium nor any party involved in creating or delivering this web site shall be liable for damages of any kind that may result from access to, or use of the information contained on, this web site, including, but not limited to, any such damages arising from errors or omissions, misprints, out-of-date information, inaccuracies, typographical or other errors appearing on this web site, any software that may be downloaded from this web site, or any damage to your computer equipment including, but not limited to, any virus that may infect your computer equipment.

MILLENNIUM MAKES NO REPRESENTATIONS OR WARRANTIES, EXPRESS OR IMPLIED, INCLUDING WITHOUT LIMITATION ANY WARRANTIES OF MERCHANTABILITY, FITNESS FOR A PARTICULAR PURPOSE OR NONINFRINGEMENT, WITH RESPECT TO THE USE OF THIS WEB SITE OR ANY INFORMATION OR SERVICES OBTAINED THROUGH THIS WEB SITE. IN NO EVENT WILL MILLENNIUM BE LIABLE FOR ANY DAMAGES OR LOSSES OF ANY KIND RESULTING DIRECTLY OR INDIRECTLY FROM ANY USE OF THIS WEB SITE OR DEFECT IN THIS WEB SITE OR ANY INFORMATION CONTAINED IN THIS WEB SITE, INCLUDING BUT NOT LIMITED TO CONSEQUENTIAL, INCIDENTAL OR OTHER INDIRECT DAMAGES.

By using this web site, you assume the risk that the information and materials on this web site may be incomplete, inaccurate, out-of-date, or may not meet your needs or requirements.

Please note that some jurisdictions may not allow the exclusion of implied warranties, so some of the above exclusions may not apply to you. Check your local laws for any restrictions or limitations regarding the exclusion of implied warranties.

Export of Information
The United States Export Controls laws prohibit the export of certain technical data and software to certain countries, territories and individuals. No content from this site may be downloaded or otherwise exported in violation of United States law.

Web Site Availability
This web site may be unavailable from time to time due to mechanical, technical, software, hardware or third-party vendor failures, updating or construction. Millennium cannot predict or control when such downtime may occur and cannot control the duration of such downtime.

Miscellaneous
These Terms and conditions are governed and interpreted pursuant to the laws of the Commonwealth of Massachusetts, United States of America, notwithstanding any principles of conflicts of law that would dictate the application of the law of another jurisdiction. If any part of these terms is unlawful, void, or unenforceable, that part will be deemed severable and will not affect the validity and enforceability of the remaining provisions. Millennium may, at its sole discretion and without notice, revise these terms at any time by updating this posting. This is the entire Agreement between the parties relating to the subject matter herein and shall not be modified except in writing signed by both parties or by a new posting by Millennium, as described above. If you have any questions about the rights and restrictions above, please contact our legal department.

Paying for Treatment

Find out how the makers of VELCADE (bortezomib) may be able to help.

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Understanding your treatment schedule

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VELCADE INFO LINE: 1-866-835-2233

Indications and Important Safety Information for VELCADE® (bortezomib)

What is VELCADE used for?

VELCADE (bortezomib) is approved for the treatment of patients with multiple myeloma (a cancer of the plasma cells). VELCADE is also approved for the treatment of patients with mantle cell lymphoma (a cancer of the lymph nodes) who have already received other treatments.

How is VELCADE administered?

VELCADE is prescribed by a physician experienced in the use of medications to treat cancer. It is administered by a healthcare professional as an injection into your vein (intravenously, or IV) or under your skin (subcutaneously). VELCADE must not be administered into your spinal fluid (intrathecally).

Who should not receive VELCADE?

Before you receive treatment with VELCADE, tell your doctor about all of your medical conditions. You should not receive VELCADE if you are allergic to bortezomib, boron, or mannitol.

What are the possible side effects of VELCADE?

VELCADE (bortezomib) can cause serious side effects, including:

  • Peripheral neuropathy. VELCADE can cause damage to the nerves, a condition called peripheral neuropathy. You may feel muscle weakness, tingling, burning, pain, and loss of feeling in your hands and feet, any of which can be severe. Tell your doctor if you notice any of these symptoms. Your doctor may change the dose and/or schedule of VELCADE or stop it altogether. If you have peripheral neuropathy before starting VELCADE, your doctor could consider giving you VELCADE subcutaneously.
  • Low blood pressure. VELCADE can cause a drop in blood pressure. Tell your doctor if you have low blood pressure, feel dizzy, or feel as though you might faint. If you are taking drugs that lower blood pressure, your medications might need to be adjusted. If you are not drinking enough liquids, your doctor may need to administer IV fluids.
  • Heart problems. Treatment with VELCADE can cause or worsen heart rhythm problems and heart failure. Your doctor may closely monitor you if you have, or are at risk for, heart disease. Tell your doctor if you experience chest pressure or pain, palpitations, swelling of your ankles or feet, or shortness of breath.
  • Lung problems. There have been reports of lung disorders in patients receiving VELCADE. Some of these events have been fatal. Tell your doctor if you experience any cough, shortness of breath, wheezing, or difficulty breathing.
  • Liver problems. If you have liver problems, it can be harder for your body to get rid of VELCADE. VELCADE has caused sudden liver failure in patients who were taking many medications or had other serious medical conditions. Symptoms of liver problems include a yellow discoloration of the eyes and skin (jaundice) and changes in liver enzymes measured in blood tests. Your doctor will closely monitor you if you have liver disease.
  • Posterior reversible encephalopathy syndrome (PRES). There have been reports of a rare, reversible condition involving the brain, called PRES, in patients treated with VELCADE. Patients with PRES can have seizures, high blood pressure, headaches, tiredness, confusion, blindness, or other vision problems. Treatment with VELCADE should be stopped in cases of PRES.
  • Gastrointestinal problems. VELCADE (bortezomib) treatment can cause nausea, vomiting, diarrhea, and constipation. If your symptoms are severe, your doctor may recommend IV fluids and/or medications.
  • Neutropenia (low levels of neutrophils, a type of white blood cell). VELCADE can cause low levels of white blood cells (infection-fighting cells). If your white blood cells become low, you can be at higher risk for infections. Tell your doctor if you develop a fever or believe you have an infection.
  • Thrombocytopenia (low levels of platelets). VELCADE can cause low levels of platelets (clot-forming cells). If platelets become very low, there is an increased risk of bleeding. Your doctor may recommend a platelet transfusion.
    You will have regular blood tests to check your cell counts during your treatment with VELCADE. If the number of these cells is very low, your doctor may change the dose and/or schedule of VELCADE.
  • Tumor lysis syndrome (TLS). TLS is a syndrome that causes a chemical imbalance in the blood that could lead to heart and/or kidney problems. TLS can occur with cancer treatments, and your doctor will be monitoring your blood and urine for any signs of this syndrome. If you develop TLS, your doctor will take appropriate steps to treat it.

More than 1 in 5 patients (20%) receiving VELCADE have experienced the following side effects: nausea, diarrhea, thrombocytopenia, neutropenia, peripheral neuropathy, fatigue, neuralgia (nerve pain), anemia, leukopenia (low levels of white blood cells), constipation, vomiting, lymphopenia (low levels of a certain type of white blood cells), rash, pyrexia (fever), and anorexia.

What other information should you discuss with your doctor?

Women should avoid becoming pregnant or breast-feeding while being treated with VELCADE (bortezomib). Discuss with your doctor when it is safe to restart breast-feeding after finishing your treatment.

You should also tell your doctor if you:

  • Have kidney disease. If you are on dialysis, your doctor will administer VELCADE after the dialysis procedure.
  • Are taking medication for diabetes. VELCADE can affect your blood glucose levels. Your doctor may require close monitoring of your blood glucose levels and change the dose of your diabetes medicine while you are being treated with VELCADE.
  • Have liver disease.
  • Are using any other medications, including prescription and over-the-counter drugs, herbal or dietary supplements, or holistic treatments. St. John’s wort should be avoided.
  • Develop a rash of any type while receiving VELCADE.

The side effects of VELCADE may impair your ability to drive or operate machinery.

These are not all of the possible side effects with VELCADE. It is important to always contact your doctor if you experience any side effects while on VELCADE. If you have any questions about VELCADE, contact your doctor. Additional information is available on the Web site VELCADE.com.

Please see the full Prescribing Information for VELCADE, including Warnings and Precautions.

© 2013 Millennium Pharmaceuticals, Inc. A wholly-owned subsidiary of Takeda Pharmaceutical Company Limited       V-12-0386 02/13